The quarterback has shown he can lead a team struggling with injuries, and now, with Christian McCaffrey back, San Francisco ...

Some new names lit up the waiver wire in Week 10, but which fantasy football breakouts are for real and which are fool's gold?

Christian McCaffrey wasn't eased back into action when he made his return to the field on Sunday afternoon against the ...

Following a lengthy holdout during training camp, Brandon Aiyuk signed a four-year, $120 million contract with the San Francisco 49ers in late August. After landing his new deal, Aiyuk and the 49ers ...

Fantasy football analyst Matt Harmon examines some of the biggest storylines coming out of Week 10's Sunday action.

Pittsburgh has won all three of Wilson’s starts while averaging 30.3 points per game with the former Super Bowl champion.

As the 49ers defeated the Tampa Bay Buccaneers in their Week 10 matchup, Kyle Shanahan gets real on Jauan Jennings' ...

San Francisco 49ers wide receiver Jauan Jennings, who missed the last two games due to a hip injury, returned to the lineup on Sunday against the Tampa ...

San Francisco QB Brock Purdy connected with the rookie, who missed the team's first six games after being shot during an ...

Welcome to the NFL, Ricky Pearsall. The 49ers' No. 31 overall pick from this year's draft didn't make it onto the field until ...

Christian McCaffrey is set to make his season debut for the San Francisco against the Tampa Bay Buccaneers on Sunday. How ...

With the stretch run of the NFL season looming, ESPN released a flurry of midseason predictions for multiple teams, including ...